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Natural (born) killer cells battle pediatric leukemia.
Researchers at Children’s Hospital Los Angeles have shown that a select team of immune-system cells from patients with leukemia can be multiplied in the lab, creating an army of natural killer cells...
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Novel vaccine decreases recurrence in HER2 breast cancer patients.
A new breast cancer vaccine candidate, (GP2), provides further evidence of the potential of immunotherapy in preventing disease recurrence. This is especially the case for high-risk patients when it is...
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New T-cell regulation discovery set to rewrite immunology text books.
To be activated, T cells must first recognize an antigen, receive appropriate costimulatory signals, and then encounter inflammatory cytokines to expand the immune response. This immune response has...
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Researchers use ‘demethylating’ precision medicine to fight cancer.
A main barrier to immune therapy success has been the tumour’s ability to keep the immune system from functioning against the cancer. The immune cells are there, however, like an unarmed army, they...
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Researchers uncover more about the elusive pericyte-tumour interaction.
Tumours are known to evade the immune system by a variety of mechanisms, one of which is the recruitment of ‘myeloid-derived suppressor cells’ (MDSC). MDSCs suppress the ability of the immune system’s...
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Role finally identified for subset of white blood cells in cancer metastasis.
The primary role of monocytes is to sense the environment and replenish the pool of tissue macrophages and dendritic cells. Recent advances in immunology research have discovered that monocytes can be...
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